The ability of OPTI-FREE® RepleniSH® MPDS to recondition soft lenses has been demonstrated in several ex vivo clinical studies that examined the wettability of lenses following daily wear.

Previously, OPTI-FREE® EXPRESS® MPDS was found to keep the lens surface wet for up to 8 hours. However, patients report wearing their lenses for an average of 13 hours. Thus, the need remains for a multi-purpose solution that maintains lens surface wettability for at least 13 hours. Due to the outstanding reconditioning properties of TearGlyde®, OPTI-FREE® RepleniSH® demonstrated the ability to maintain moisture on the lens surface at 14 hours.

Wettability was measured by the dispersion of moisture over contact lenses that have been soaked overnight in a multi-purpose solution and worn in the eye for a pre-specified length of time. A lower wetting angle is correlated with a greater ability to retain moisture.

OPTI-FREE® RepleniSH® maintains a low wetting angle at 14 hours of wear.⁵

1. Tested on silicone hydrogel lenses in a 14-hour study, data on file, Alcon Laboratories, Inc.
2. Meadows D, Ketelson H, et al. Impact of Water Content and Care Regimen on the long term ex-vivo clinical wettability of soft contact lenses, Poster presented at AAO, Dec 2005.
3. Ketelson H, Meadows, D, et al. Enhancing Wettability with Multi-purpose Solutions. Review of Cornea & Contact Lenses. Jan/Feb 2005.
4. 8 hour Study, Ketelson H, Meadows D, Stone R. Dynamic wetting behavior of pHEMA-MAA and silicone hydrogel contact lenses. Alcon Laboratories, Inc. Poster presented at: ARVO 2004.
5. Data on file. Alcon Laboratories, Inc.