With ongoing patient wear, protein deposits build up on hydrogel contact lenses. These proteins, specifically the major tear protein lysozyme, accumulate rapidly on Group IV lenses.
The outstanding cleaning ability of OPTI-FREE® RepleniSH® MPDS has been confirmed in additional studies. OPTI-FREE® RepleniSH® removes the greatest amount of lysozyme from Group IV lenses.1
As proteins accumulate on lenses, ocular discomfort can occur, leading to decreased wearing time. The efficacy of OPTI-FREE® RepleniSH® MPDS in the removal of lens proteins has been determined using in vitro lysozyme deposition models and ex vivo clinical studies that compared OPTI-FREE® RepleniSH® with marketed multi-purpose solutions.
The cleaning agent used in OPTI-FREE® RepleniSH® is citrate, which helps remove the biological deposits from the lens surface.
Among solutions tested, OPTI-FREE® RepleniSH® MPDS demonstrated the greatest cleaning efficacy, defined as a percentage of lysozyme removed with cleaning. After a 7-day regimen of immersion in lysozyme solution followed by a regimen of soaking, OPTI-FREE® RepleniSH® demonstrated greater cleaning efficacy than other studied solutions.1
- Two week, masked, crossover study design2
- No significant differences were found between OPTI-FREE® RepleniSH® and Clear Care* in investigator ratings of lens deposits.
- Hong B, Stauffer P, Meadows D, Keith D. Assessment of cleaning efficacy of contact lens multi-purpose disinfecting solution by in vitro lysozyme deposition model. Poster presented at: ARVO 2005.
- Data on file, Alcon Laboratories, Inc.
